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Climate combines technological, behavioural science, and governance approaches to energy transition, mitigation, adaptation, and circular innovation. Climate aims to make a systemic contribution to mitigation and adaptation. The focus is on climate-resilient infrastructure, energy transition, circular systems, and planetary health. University of Twente research supports the European climate adaptation trajectory and the Dutch climate goals, with portfolios focusing on topics such as negative emissions and weather extremes.

With chip technology, we contribute to strategic autonomy and key technologies. The UT distinguishes itself through integrated expertise in design, production, materials development, and societal reflection. Chip technology is crucial for technological sovereignty. The UT works across the entire spectrum: from chip design to production and materials, supported by high-end infrastructure (such as NanoLab and New Origin). Together with partners, the UT contributes to national programs and the European Chips Act.

Health focuses on personal well-being and sustainable healthcare systems. UT develops innovative technologies and methods that support prevention, diagnosis, and treatment in collaboration with medical, societal, and industrial partners. Health encompasses both individual and systemic challenges, from personalised medicine and digital health to the resilience of healthcare infrastructures. Within this domain, UT advances areas such as personalised eHealth, Medical Robotics, and Health Data Science. Collaboration with hospitals, policy makers, and industry ensures that innovations contribute directly to better care and healthier lives, coordinated by the UT TechMed Centre.

Safety & Security focuses on societal and technological resilience. The University of Twente develops physical and digital infrastructures, prevention strategies, and total defense solutions in collaboration with public and private partners. Security encompasses societal, digital, and physical safety. Within this domain, the University of Twente works on resilient information systems, infrastructures, and a safe society through programs such as Cyber Resilience and Safe Engineered Systems. The integration with the Ministry of Defence is shaped through multidisciplinary portfolios and partnerships.

The Digital Society Institute performs scientific research in technology that is essential for digitalization, on methods and techniques for integrating digital technology in our environments, and in how we can come to intelligent, well-informed decision making. An important aspect of our mission is to conduct research that has an impact on society.

MESA+ is one of the world’s leading research institutes on nanostructures, nanomaterials, nanosystems and nanodevices. Embracing a cross-disciplinary approach and benefiting from the NanoLab - infrastructure that ranks among the very best on the globe - over 500 researchers deliver high quality, competitive and frequently ground-breaking research. The results are evident in our numerous publications as well as in various high-profile achievements.

The TechMed Centre is a leading innovation hub in the health-tech domain with state-of-the-art infrastructure, ranging from research labs, preclinical testbeds and simulated hospital environments to the actual healthcare system. Its mission is to enable sustainable and personalised health by means of technology. The TechMed Centre improves healthcare through research & development, education and collaboration in a global network.